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The '''anterior cingulate cortex''' (ACC) is the frontal part of the [[cingulate cortex]], that resembles a "collar" form around the [[corpus callosum]], the fibrous bundle that relays neural signals between the right and left [[cerebral hemisphere]]s of the brain. It consists of Brodmann areas 24, 32 and 33. It appears to play a role in a wide variety of [[Autonomic nervous system|autonomic]] functions, such as regulating blood pressure and heart rate, as well as rational cognitive functions, such as reward anticipation, [[Decision Making|decision making]], empathy<ref>http://ccare.stanford.edu/node/89</ref> and emotion.<ref>Decety, J., & Jackson, P.L. (2004). The functional architecture of human empathy. Behavioral and Cognitive Neuroscience Reviews, 3, 71-100.</ref><ref>Jackson P.L., Brunet E., Meltzoff A.N., Decety J., 2006 Empathy examined through the neural mechanisms involved in imagining how I feel versus how you feel pain: An event-related fMRI study, ''Neuropsychologia'', 44, pp. 752–61</ref>
In decision making it is thought to detect conflicts between two deductions<ref>[http://www.nature.com/neuro/journal/v10/n10/abs/nn1979.html Neurocognitive correlates of liberalism and conservatism, 2007, Amodio et al. Nature neuroscience] ([http://www.talyaron.com/wiki/index.php?title=Neurocognitive_correlates_of_liberalism_and_conservatism_2007 Summery in Hebrew])</ref><ref>[http://cercor.oxfordjournals.org/content/18/4/796.full Jin Fan, Patrick R. Hof, Kevin G. Guise, John A. Fossella and Michael I. Posner, The Functional Integration of the Anterior Cingulate Cortex during Conflict Processing, Cerebral Cortex, Volume 18 Issue 4, p. 796-805.]</ref> and [[value evaluation in the brain|evaluating]] the [[rewards]] of actions<ref>[http://www.nature.com/neuro/journal/v9/n7/abs/nn1724.html Kennerley et al., Optimal decision making and the anterior cingulate cortex, Nature Neuroscience 9, 940 - 947 (2006)] </ref>. On the integration of these finding please read this [http://www.lamsade.dauphine.fr/~mousseau/pmwiki-2.1.5/uploads/Bibliographie/13.pdf article].
In order to resolve an emotional conflict the rostal[[ACC]] inhibits the amygdala (or [[FFFF]] mechanism)<ref>[http://citeseerx.ist.psu.edu/viewdoc/download?doi=10.1.1.126.1555&rep=rep1&type=pdf Amit Etkin, Tobias Egner, Daniel M. Peraza, Eric R. Kandel and Joy Hirsch, Resolving Emotional Conflict: A Role for the Rostral Anterior Cingulate Cortex in Modulating Activity in the Amygdala, Neuron 51, 1–12, September 7, 2006]</ref>. This is strengthing by the findings that in panic disorder, the volume of the the ACC is reduced, <ref>[https://www.slicer.org/slicerWeb/images/2/2c/Asami-PsychiatryClinNeurosci2008.pdf Takeshi et al., Anterior cingulate cortex volume reduction in patients with panic disorder, Psychiatry and Clinical Neurosciences 2008; 62: 322–330]</ref> .