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Ventral stratium

Brain regions.png

The Ventral Stratium is positivly corrlated with effort, and thus it is sought to be involved in motivation[1]. It is involved in reward system[2]. release of dopamine in the ventral stratium cause good feeling. Dopamine depletion in ventral striatum reduces propensity for physical effort [3]

References

  1. Mechanisms Underlying Motivation of Mental Versus Physical Effort. PLoS Biology, 2012; 10 (2): e1001266 DOI: 10.1371/journal.pbio.1001266.
  2. Gregorios-Pippas L, Tobler PN, Schultz W (March 2009). "Short-term temporal discounting of reward value in human ventral striatum". J. Neurophysiol. 101 (3): 1507–23. doi:10.1152/jn.90730.2008. PMC 2666398. PMID 19164109.
  3. Salamone JD, Correa M, Farrar A, Mingote SM. Effort-related functions of nucleus accumbens dopamine and associated forebrain circuits. Psychopharmacology. 2007;191: 461– 482.