Novelty seeking may be triggered by Reward Prediction Error ([[RPE]]). much support has accumulated for an association between novelty seeking (Cloninger et al., 1994<ref>Cloninger, C.R., Pryzbeck, T.R., Svrakic, D.M., Wetzel, R.D., 1994. The Temperament and Character Inventory (TCI): A Guide to its Development and Use. Centre for Psychobiology of Personality, St. Louis Missouri.</ref>) and dopaminergic activity (see e.g. Savitz and Ramesar, 2004 for a review<ref>Savitz, J.B., Ramesar, R.S., 2004. Genetic variants implicated in personality: a review of the more promising candidates. Am. J. Med. Genet. Pt. B 131B, 20–32.</ref>). Adolescent with conduct disorder (aggressive disorder) had lower activation of the [[ACC]], lower sociomoral judgment and higher need for [[novelty seeking]]<ref>[http://www.sciencedirect.com/science/article/pii/S0022395606000161 Christina Stadlera, Philipp Sterzerb, Klaus Schmeckc, Annette Krebsa, Andreas Kleinschmidt, Fritz Poustka, Reduced anterior cingulate activation in aggressive children and adolescents during affective stimulation: Association with temperament traits, 2007]</ref>.