Nucleus accumbens play part in reward sytem<ref>[http://www.jneurosci.org/content/33/8/3434.full Kyle K. Pitchers1,Vincent Vialou,Eric J. Nestler,Steven R. Laviolette, Michael N. Lehman and Lique M. Coolen, 2013, Natural and Drug Rewards Act on Common Neural Plasticity Mechanisms with ΔFosB as a Key Mediator]</ref>. Natural reward behaviors and drug reward converge on a common neural pathway, the mesolimbic dopamine (DA) system, in which the nucleus accumbens (NAc) plays a central role<ref>Kelley AE (2004) Memory and addiction: shared neural circuitry and molecular mechanisms. Neuron 44:161–179.</ref>