LC-NE system and ACC may modulate aroused attention in a novel environment and new social environment[1]. LC receives prominent, direct inputs from the anterior cingulate (ACC) and orbitofrontal cortices (OFC), both of which are thought to monitor task-related (explotation) utility[2]
References
- ↑ Heinrich S Gompf, Christine Mathai, Patrick M Fuller, David A Wood, Nigel P Pedersen, Clifford B Saper, and Jun Lu, 2011, Locus coeruleus (LC) and anterior cingulate cortex sustain wakefulness in a novel environment, Neurosci. Oct 27, 2010; 30(43): 14543–14551.
- ↑ Gary Aston-Jones, and Jonathan D. Cohen. 2005, AN INTEGRATIVE THEORY OF LOCUS COERULEUS-NOREPINEPHRINE FUNCTION: Adaptive Gain and Optimal Performance, Annual Review of Neuroscience Vol. 28: 403-450