Difference between revisions of "Nural decision makeing - brain"
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Revision as of 00:18, 30 June 2014
Hormones effects
Food
There are substantial hormonal influences on behavior. For example, circulating hormones such as leptin and ghrelin act as satiety and hunger signals, reporting the status of body energy reserves (e.g. adipose tissue), energy requirements, and acute nutrient intake to hypothalamic and midbrain targets in the central nervous system that regulate feeding behavior[1]. They also act on brain regions (in particular dopaminoceptive areas) implicated in human decision-making[2][3].
Metabolic state itself may thus directly affect the neural expression of preference, exemplified by findings that physiological state influence preferences for economic risk in humans[4]
Impulsivity
Seratonine deplition[5] and NMDA antagonism [6]promote impulsivity
Refrerences
- ↑ Korotkova, Sergeeva, Eriksson et al., 2003
- ↑ Hommel, Trinko, Sears et al., 2006
- ↑ Krügel, Schraft, Kittner et al., 2003
- ↑ Symmonds M, Emmanuel J, Drew M, Batterham R, Dolan R. Metabolic state alters economic decision-making under risk in humans. PLoS ONE. 2010b; 5: e11090.
- ↑ Denk F, Walton M, Jennings K, Sharp T, Rushworth M, Bannerman D. Differential involvement of serotonin and dopamine systems in cost-benefit decisions about delay or effort. Psychopharmacology. 2005;179: 587– 596.
- ↑ Floresco SB, Tse MTL, Ghods-Sharifi S. Dopaminergic and glutamatergic regulation of effort-and delay-based decision-making.